Mohammad H. Forouzanfar, Ashkan Afshin, Lily Alexander, H Ross Anderson et al.
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debat...
Theo Vos, Ryan M Barber, Brad Bell, Amelia Bertozzi-Villa et al.
Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities f...
Christina Fitzmaurice, Degu Abate, Naghmeh Abbasi, Hedayat Abbastabar et al.
<h3>Importance</h3> Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the P...
Christopher J L Murray, Ryan M Barber, Kyle J Foreman, Ayşe Abbasoğlu Özgören et al.
Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex grou...
Christopher J L Murray, Cristiana Abbafati, Kaja Abbas, Mohammad Hossein Abbasi et al.
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first ...
Akram Pourshams, Sadaf G Sepanlou, Kevin S Ikuta, Catherine Bisignano et al.
BACKGROUND: Worldwide, both the incidence and death rates of pancreatic cancer are increasing. Evaluation of pancreatic cancer burden and its global, regional, and national patterns is crucial to policy making and better resource allocation for controlling pancreatic cancer risk factors, developing ...
Xin Wang, You Li, Katherine L. O’Brien, Shabir A. Madhi et al.
BACKGROUND: Seasonal influenza virus is a common cause of acute lower respiratory infection (ALRI) in young children. In 2008, we estimated that 20 million influenza-virus-associated ALRI and 1 million influenza-virus-associated severe ALRI occurred in children under 5 years globally. Despite this s...
Shafaqat Ali, Zohaib Abbas, Muhammad Rizwan, Ihsan Elahi Zaheer et al.
Heavy-metal (HM) pollution is considered a leading source of environmental contamination. Heavy-metal pollution in ground water poses a serious threat to human health and the aquatic ecosystem. Conventional treatment technologies to remove the pollutants from wastewater are usually costly, time-cons...
Masayuki Teramoto, George Patton, Karly Cini, Yohannes Abate et al.
BACKGROUND: Despite the well documented consequences of obesity during childhood and adolescence and future risks of excess body mass on non-communicable diseases in adulthood, coordinated global action on excess body mass in early life is still insufficient. Inconsistent measurement and reporting a...
Roy Burstein, Nathaniel J Henry, Michael L. Collison, Laurie B. Marczak et al.
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable child deaths by 2030-we need consistently estimated data at the subnational ...
Kuldeep Dhama, Firzan Nainu, Andri Frediansyah, Mohd. Iqbal Yatoo et al.
Newly emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are continuously posing high global public health concerns and panic resulting in waves of coronavirus disease 2019 (COVID-19) pandemic. Depending on the extent of genomic variations, mutations and adaptation, fe...
Ali A. Rabaan, Shamsah H. Al-Ahmed, Javed Muhammad, Amjad Khan et al.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious tentacles of the disease have been disseminated worldwide with unknown complications and repercussions. Advanced COVID-19 syndrome is ...
T. K. Goswami, Mithilesh Singh, Manish Dhawan, Saikat Mitra et al.
Autoimmune diseases are caused when immune cells act against self-protein. This biological self-non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response regulators and play a pivotal role in immune to...
Ali A. Rabaan, Raghavendra Tirupathi, Anupam Sule, Jehad Aldali et al.
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease 2019 (COVID-19). However, many scientists disagree, and it is essential to understand that several factors and variables can cause a false-negative test. In this context, cycle threshold (Ct) values are being ...
Lisa M Force, Jonathan M Kocarnik, Miranda L May, Kayleigh Bhangdia et al.
Background Cancer is a leading cause of death globally. Accurate cancer burden information is crucial for policy planning, but many countries lack up-to-date cancer surveillance data. To inform global cancer-control efforts, we used the Global Burden of Diseases, Injuries, and Risk Factors Study (GB...