Sergei Põlme, Kessy Abarenkov, R. Henrik Nilsson, Björn D. Lindahl et al.
TEST 02 - Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.
Intza Garin, Emma L. Edghill, İldem Akerman, Oscar Rubio‐Cabezas et al.
Heterozygous coding mutations in the INS gene that encodes preproinsulin were recently shown to be an important cause of permanent neonatal diabetes. These dominantly acting mutations prevent normal folding of proinsulin, which leads to beta-cell death through endoplasmic reticulum stress and apopto...
Uzma Z. Rizvi
Abstract Acknowledgement I would like to thank my colleagues and friends Praveena Gullapalli and Benjamin Porter for the comments and insights that have helped shaped this piece in its initial stages. Additionally, this work has benefited from my conversations with Sandra Scham. I would also like to...
Achilleas Floudas, Sean P. Saunders, Tara Moran, Christian Schwartz et al.
Abstract Atopic dermatitis (AD) is a common inflammatory skin disease affecting up to 20% of children and 3% of adults worldwide and is associated with dysregulation of the skin barrier. Although type 2 responses are implicated in AD, emerging evidence indicates a potential role for the IL-17A signa...
Matthew A. French, Fiona Barker, Ruzka R. Taruc, Ansariadi Ansariadi et al.
BACKGROUND: The intense interactions between people, animals and environmental systems in urban informal settlements compromise human and environmental health. Inadequate water and sanitation services, compounded by exposure to flooding and climate change risks, expose inhabitants to environmental c...
Stephen Wright, Fiona M. O’Prey, Derrick J. Rea, Rick Plumb et al.
OBJECTIVE: Impaired flow-mediated dilation (FMD) occurs in disease states associated with atherosclerosis, including SLE. The primary hemodynamic determinant of FMD is wall shear stress, which is critically dependent on the forearm microcirculation. We explored the relationship between FMD, diastoli...
Newton A C S Wong, L. Brett, Michael Stewart, Andrew Leitch et al.
Thymidylate synthase (TS) is a key enzyme in DNA synthesis and is inhibited by metabolites of the chemotherapeutic agent 5-fluorouracil (5FU). Nuclear expression of TS in human tissue in vivo has not been characterised and its clinicopathological correlates in malignancy are unknown. 52 cases of pri...
Paula M. Gilmore, Nuala McCabe, Jennifer E. Quinn, Richard D. Kennedy et al.
BRCA1 has been implicated in a number of cellular processes, including transcriptional regulation, DNA damage repair, cell cycle arrest, and apoptosis. We identified mitogen-activated protein kinase (MAPK) kinase kinase 3 (MEKK3), an upstream regulator of the c-Jun NH(2)-terminal kinase/stress-activ...
Sergei Põlme, Kessy Abarenkov, R. Henrik Nilsson, Björn D. Lindahl et al.
There were errors in the name of author László G. Nagy and in affiliation no. 31 in the original publication. The original article has been corrected.
Mohamed El-Shazly, Bernadette P. Trainor, George Kernohan, Ian C. Turner et al.
OBJECTIVE: To investigate if those responsible for screening for neonatal hip instability are using acceptable manual hip stress tests as described by Ortolani and Barlow. METHOD: A video camera was used to record the technique of 35 personnel who were responsible for screening. They examined both a...
Rebecca Sims, Sarah Dwyer, Denise Harold, Amy Gerrish et al.
We sought to investigate the contribution of extended runs of homozygosity in a genome-wide association dataset of 1,955 Alzheimer's disease cases and 955 elderly screened controls genotyped for 529,205 autosomal single nucleotide polymorphisms. Tracts of homozygosity may mark regions inherited from...
Kurt T. K. Giuliani, Purba Nag, Benjamin C. Adams, Xiangju Wang et al.
Abstract Hypoxia and interleukin (IL)-1β are independent mediators of tubulointerstitial fibrosis, the histological hallmark of chronic kidney disease (CKD). Here, we examine how hypoxia and IL-1β act in synergy to augment maladaptive proximal tubular epithelial cell (PTEC) repair in human CKD. Ex v...
Andrew Johnston, Jeroen Veldman, Robert G. Eccles, Simon Deakin et al.
The current model of corporate governance needs reform. There is mounting evidence that the practices of shareholder primacy drive company directors and executives to adopt the same short time horizon as financial markets. Pressure to meet the demands of the financial markets drives stock buybacks, ...
Jonathan Robinson, Will Woods, Sumie Leung, Jordy Kaufman et al.
Abstract Predictive coding theories of perception suggest the importance of constantly updated internal models of the world in predicting future sensory inputs. One implication of such models is that cortical regions whose function is to resolve particular stimulus attributes should also signal pred...
Michal Shteinberg, Joseph Rivlin, Michal Gur, Muriel Konopnicki et al.
Haptoglobin (Hp), a heme-Iron chelator, has different isoforms which are associated with variable tendency toward infections: Hp 1-1, Hp 2-1, and Hp 2-2. Cystic fibrosis (CF) outcomes are variable and influenced by genetic and environmental factors. The aim of this study was to determine whether Hp ...
Andrew Bowie, D. Owens, P. Collins, Alan Johnson et al.
Jecolia Mengesha, Jabir Abdulahi, Theresa Tawiah, Bilal Ahmed Usmani et al.
The Maternal Immunisation Readiness Network in Africa and Asia (MIRNA), is committed to assessing readiness and facilitating the introduction of RSV and GBS maternal immunization in partner countries, which include Bangladesh, Ethiopia, Ghana, Kenya, Nigeria, Pakistan, South Africa, and Uganda. Each...
Sajida Parveen, Muhammad Imran Nisar, Jabir Abdulahi, Wafa Zehra Jamal et al.
The Maternal Immunisation Readiness Network in Africa and Asia (MIRNA), is committed to assessing readiness and facilitating the introduction of RSV and GBS maternal immunization in partner countries, which include Bangladesh, Ethiopia, Ghana, Kenya, Nigeria, Pakistan, South Africa, and Uganda. Each...
Ishrat Jabeen, Avijit Sarker Jyoti, Rabia Akter Munni, P. P. Dhar et al.
Being a neglected tropical disease and a major public health concern, scabies is undoubtedly common and contagious specially for low socio-economic and densely populated areas like us. In spite of high burden, the epidemiology has not been well assessed specially for Dhaka, Bangladesh. Therefore, th...
James Heckman, P Edward, Kevin Lazear, Murphy et al.
Previous article FreeIndex to Volume 126PDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinked InRedditEmailQR Code SectionsMoreArticles and NotesAguiar, Luis, and Joel Waldfogel. Quality Predictability and the Welfare Benefits from New...