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Results for “"Deepak Kaushik"”

21+ results

Blockchain and artificial intelligence technology in e-Health

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Priti Tagde, Sandeep Tagde, Tanima Bhattacharya, Pooja Tagde et al.

Journal: Environmental Science and Pollution ResearchYear: 2021Citations: 262

Blockchain and artificial intelligence technologies are novel innovations in healthcare sector. Data on healthcare indices are collected from data published on Web of Sciences and other Google survey from various governing bodies. In this review, we focused on various aspects of blockchain and artif...

Physical SciencesComputer ScienceInformation SystemsOpen Access
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Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers

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Md. Tanvir Kabir, Md. Habibur Rahman, Rokeya Akter, Tapan Behl et al.

Journal: BiomoleculesYear: 2021Citations: 204

Cancer is a major burden of disease globally. Each year, tens of millions of people are diagnosed with cancer worldwide, and more than half of the patients eventually die from it. Significant advances have been noticed in cancer treatment, but the mortality and incidence rates of cancers are still h...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

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Md. Habibur Rahman, Rokeya Akter, Tanima Bhattacharya, Mohamed M. Abdel‐Daim et al.

Journal: Frontiers in PharmacologyYear: 2020Citations: 181

Alzheimer’s disease (AD) is a progressive cortex and hippocampal neurodegenerative disease which ultimately causes cognitively impaired decline in patients. The AD pathogen is a very complex process, including aggregation of Aβ (β-amyloid peptides), phosphorylation of tau-proteins, and chronic infla...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy

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Ashwani Arya, Rubal Chahal, Rekha Rao, Md. Habibur Rahman et al.

Journal: BiomoleculesYear: 2021Citations: 107

Alzheimer’s disease (AD) is a gradually growing irreversible illness of the brain that almost affects every fifth person (aged > 80 years) in the world. World Health Organization (WHO) also revealed that the prevalence of this disease will enhance (upto double) significantly upto 2030. The poor c...

Health SciencesMedicinePharmacologyOpen Access
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Ageratum conyzoides L. and Its Secondary Metabolites in the Management of Different Fungal Pathogens

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Rubal Chahal, Arun Nanda, Esra Küpeli Akkol, Eduardo Sobarzo‐Sánchez et al.

Journal: MoleculesYear: 2021Citations: 68

Ageratum conyzoides L. (Family—Asteraceae) is an annual aromatic invasive herb, mainly distributed over the tropical and subtropical regions of the world. It owns a reputed history of indigenous remedial uses, including as a wound dressing, an antimicrobial, and mouthwash as well as in treatment of ...

Life SciencesAgricultural and Biological SciencesFood ScienceOpen Access
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Improved Pharmacodynamic Potential of Rosuvastatin by Self-Nanoemulsifying Drug Delivery System: An in vitro and in vivo Evaluation

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Ravinder Verma, Ajeet Kaushik, Rafa Almeer, Md. Habibur Rahman et al.

Journal: International Journal of NanomedicineYear: 2021Citations: 67

Purpose: The purpose of this proposed research was to investigate a nano-formulation developed using self-nanoemulsifying drug delivery system (SNEDDS) to improve the pharmacodynamic potential of rosuvastatin by assisting its transportation through lymphatic circulation. Methods: The utilized lipids...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmaceutical ScienceOpen Access
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Exploration of therapeutic applicability and different signaling mechanism of various phytopharmacological agents for treatment of breast cancer

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Vandana Singh, Kuldeep Kumar, Deepika Purohit, Ravinder Verma et al.

Journal: Biomedicine & PharmacotherapyYear: 2021Citations: 61

Cancer is one of the most dreaded diseases characterized by uncontrolled proliferation of abnormal cells that occurs due to impairment of cell division and apoptosis process. Cancer is categorized into several types on the basis of affected organs and breast cancer (BC) is the most predominant cause...

Life SciencesImmunology and MicrobiologyImmunologyOpen Access
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Delineation of Neuroprotective Effects and Possible Benefits of AntioxidantsTherapy for the Treatment of Alzheimer’s Diseases by Targeting Mitochondrial-Derived Reactive Oxygen Species: Bench to Bedside

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Vaibhav Walia, Deepak Kaushik, Vineet Mittal, Kuldeep Kumar et al.

Journal: Molecular NeurobiologyYear: 2021Citations: 45

Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients and is characterized by progressive neuronal degeneration and impairment in memory, language, etc. AD is characterized by the deposition of senile plaque, accumulation of fibrils, and neurofibrillary tangles ...

Health SciencesMedicinePhysiology
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Curcumin as a great contributor for the treatment and mitigation of colorectal cancer

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Chenmala Karthika, Balaji Hari, Vignesh Mano, Arun Radhakrishnan et al.

Journal: Experimental GerontologyYear: 2021Citations: 43

Cancer is one of the life-taking diseases worldwide and among cancer-related death; colorectal cancer is the third most. Though conventional methods of treatment are available, multidrug resistance and side effects are predominant. Physicians and scientists are working side by side to develop an eff...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Medicine
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Nanocapsules: An Emerging Drug Delivery System

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Deepika Purohit, Pawan Jalwal, Deeksha Manchanda, Sapna Saini et al.

Journal: Recent Patents on NanotechnologyYear: 2022Citations: 28

BACKGROUND: Controlled drug release and site-specific delivery of drugs make nanocapsules the most approbative drug delivery system for various kinds of drugs, bioactive, protein, and peptide compounds. Nanocapsules (NCs) are spherical shape microscopic shells consisting of a core (solid or liquid) ...

Health SciencesMedicineOncology
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Novel coronavirus pathogen in humans and animals: an overview on its social impact, economic impact, and potential treatments

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Rokeya Akter, Md. Habibur Rahman, Tanima Bhattacharya, Deepak Kaushik et al.

Journal: Environmental Science and Pollution ResearchYear: 2021Citations: 28

In the light of thousands of infections and deaths, the World Health Organization (WHO) has declared the outbreak of coronavirus disease (COVID-19) a worldwide pandemic. It has spread to about 22 million people worldwide, with a total of 0.45 million expiries, limiting the movement of most people wo...

Health SciencesMedicineInfectious DiseasesOpen Access
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Chemo-Preventive Action of Resveratrol: Suppression of p53—A Molecular Targeting Approach

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Rokeya Akter, Md. Habibur Rahman, Deepak Kaushik, Vineet Mittal et al.

Journal: MoleculesYear: 2021Citations: 26

Extensive experimental, clinical, and epidemiological evidence has explained and proven that products of natural origin are significantly important in preventing and/or ameliorating various disorders, including different types of cancer that researchers are extremely focused on. Among these studies ...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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COVID-19, the firestone in 21st century: a review on coronavirus disease and its clinical perspectives

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Chenmala Karthika, Reddi Mohana Krishna, Md. Habibur Rahman, Rokeya Akter et al.

Journal: Environmental Science and Pollution ResearchYear: 2021Citations: 14

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak began in late 2019 in Wuhan, China, and have since spread globally. Deep sequencing analysis identified the disease within a few weeks, and on February 11, the World Health Organization (WHO) named it “COVID-19 caused by SARS-...

Health SciencesMedicineInfectious DiseasesOpen Access
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Statistically Designed Extraction of Herbs Using Ultrasound Waves: A Review

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Ashwani Arya, Rubal Chahal, Arun Nanda, Deepak Kaushik et al.

Journal: Current Pharmaceutical DesignYear: 2021Citations: 14

BACKGROUND: Extraction is the foremost step to isolate the natural constituents from a medicinal plant and leads the process of development of herbal formulation from bench to bed. INTRODUCTION: In the field of extraction, the optimization approach helps in achieving better yield and quality where a...

Health SciencesMedicineOncology
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Development of Biocompatible Nanoparticles of Tizanidine Hydrochloride in Orodispersible Films: In vitro Characterization, Ex vivo Permeation, and Cytotoxic Study on Carcinoma Cells

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Rohit Dutt, Deepak Kaushik, Suhani Sinha, Sonia Thapa et al.

Journal: Current Drug DeliveryYear: 2022Citations: 13

BACKGROUND: The main limitations of the therapeutic effectiveness of tizanidine hydrochloride (TNZ) are its low bioavailability due to its tendency to undergo first-pass metabolism and short biological half-life. These factors make it an ideal candidate for formulating orally disintegrating films. O...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmaceutical Science
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Multifunctional Patented Nanotherapeutics for Cancer Intervention: 2010-Onwards

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Parijat Pandey, Hitesh Chopra, Deepak Kaushik, Ravinder Verma et al.

Journal: Recent Patents on Anti-Cancer Drug DiscoveryYear: 2022Citations: 12

Even today, cancer is one of the prominent leading causes of death worldwide. However, there are a couple of treatment options available for management, but the adverse effects are more prominent as compared to therapeutic effects. Therefore, there is a need to design some midway that may help to by...

Physical SciencesMaterials ScienceBiomaterials
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BE-SMART (Basal Early Strategies to Maximize HbA1c Reduction with Oral Therapy): Expert Opinion

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Sarita Bajaj, Ashok Kumar Das, Sanjay Kalra, Rakesh Sahay et al.

Journal: Diabetes TherapyYear: 2019Citations: 10

The past three decades have seen a quadruple rise in the number of people affected by diabetes mellitus worldwide, with the disease being the ninth major cause of mortality. Type 2 diabetes mellitus (T2DM) often remains undiagnosed for several years due to its asymptomatic nature during the initial ...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Morphological groupings within Euphlyctis (Anura: Dicroglossidae) and description of a new species from the surroundings of Thattekad Bird Sanctuary, Kerala, India

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K.P. DINESH, B. H. Channakeshavamurthy, P. Deepak, Avrajjal Ghosh et al.

Journal: ZootaxaYear: 2021Citations: 8

The skittering frog genus Euphlyctis is known to have a distribution range from Arabian Peninsula to Bangladesh through India and Sri Lanka. Although species descriptions were initiated about two centuries ago in the genus with a small number of species described, taxonomic identities and genetic in...

Physical SciencesEnvironmental ScienceGlobal and Planetary ChangeOpen Access
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Unravelling the photoprotective effects of freshwater alga Nostoc commune Vaucher ex Bornet et Flahault against ultraviolet radiations

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Saurabh Bhatia, Ahmed Al‐Harrasi, Tapan Behl, Md. Khalid Anwer et al.

Journal: Environmental Science and Pollution ResearchYear: 2021Citations: 8

Several studies have suggested the direct relationship between skin complications, air pollution, and UV irradiation. UVB radiations cause various skin complications such as skin aging, skin inflammation, and skin cancer. The current study is designed to develop an ultraviolet (UV) absorbing MAA-loa...

Life SciencesAgricultural and Biological SciencesEcology, Evolution, Behavior and Systematics
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Cyclodextrin-Based Arsenal for Anti-Cancer Treatments

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Hitesh Chopra, Ravinder Verma, Sakshi Kaushik, Jatin Parashar et al.

Journal: Critical Reviews in Therapeutic Drug Carrier SystemsYear: 2022Citations: 7

Anti-cancer drugs are mostly limited in their use due to poor physicochemical and biopharmaceutical properties. Their lower solubility is the most common hurdle limiting their use upto their potential. In the recent years, the cyclodextrin (CD) complexation have emerged as existing approach to overc...

Physical SciencesMaterials ScienceBiomaterials
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