Kamala Thriemer, Albino Bobogare, Benedikt Ley, Clarice Samo Gudo et al.
The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these ...
Hyun‐Cheol Lee, Eun‐Seo Lee, Md Bashir Uddin, Tae‐Hwan Kim et al.
ARSs are essential enzymes in translation that link specific amino acids to their cognate tRNAs. In higher eukaryotes, some ARSs possess additional, noncanonical functions in the regulation of cell metabolism. Here, we report a novel noncanonical function of WRS in antiviral defense. WRS is rapidly ...
Sang‐Hee Cho, Hyun‐Jeong Shim, Mi‐Ra Park, Jina Choi et al.
Abstract Galectin 3-binding protein (LGALS3BP, also known as 90K) is a multifunctional glycoprotein involved in immunity and cancer. However, its precise role in colon inflammation and tumorigenesis remains unclear. Here, we showed that Lgals3bp −/− mice were highly susceptible to colitis and colon ...
Rajendra Acharya, Ashraf Akintayo Akintola, Matabaro Joseph Malekera, Patrick Kamulegeya et al.
The fall armyworm, Spodoptera frugiperda, is an important agricultural pest native to tropical and subtropical regions of the Western Hemisphere, and has invaded Africa and further spread into most countries of Asia within two years. Here, we analyzed the genetic variation of invaded populations by ...
Jae Hoon Kim, Prasanna Weeratunga, Myun Soo Kim, Chamilani Nikapitiya et al.
BACKGROUND: Cortex Phellodendri (C. Phellodendri), the dried trunk bark of Phellodendron amurense Ruprecht, has been known as a traditional herbal medicine, showing several bioactivities. However, antiviral activity of C. Phellodendri aqueous extract (CP) not reported in detail, particularly aiming ...
Md. Azizul Haque, Chung Eun Hwang, Su Cheol Kim, Du Yong Cho et al.
This study is aimed to reveal the molecular incidence of organophosphorus insecticides degradation during the fermentation of Korean food yeulmu-mulkimchi. To this end, two opdA and opdE which consist of 930 and 894 bp that encode 309 and 297 amino acids, respectively, were cloned from the Leuconost...
Md. Akil Hossain, Seung‐Jin Lee, Jiyong Park, Md. Ahsanur Reza et al.
Ethnopharmacological relevance Nymphaea tetragona is a widely distributed ornamental species with ethnomedicinal uses in the treatment of diarrhea, dysentery, eruptive fevers, and infections. The anti-infectious activities of this herb have already been assessed to clarify its traditional use as a m...
Jaehoon Kim, Min-Eun Park, Chamilani Nikapitiya, Tae‐Hwan Kim et al.
FAS-associated factor-1 (FAF1) is a component of the death-inducing signaling complex involved in Fas-mediated apoptosis. It regulates NF-κB activity, ubiquitination, and proteasomal degradation. Here, we found that FAF1 positively regulates the type I interferon pathway. FAF1gt/gt mice, which defic...
Chung Eun Hwang, Md. Azizul Haque, Jin Hwan Lee, Yeong Hun Song et al.
This study evaluated the changes in γ-aminobutyric acid (GABA) and isoflavone aglycone contents from soy powder yogurt (SPY) due to sprouting of soybean (1 cm) and fermentation with Lactobacillus brevis. The levels of GABA and the aglycone form increased, and the glutamate decarboxylase and β-glucos...
Chae‐Seok Lim, Min Jung Kim, Ja Eun Choi, Md. Ariful Islam et al.
Heterogeneity in the etiopathology of autism spectrum disorders (ASD) limits the development of generic remedies, requires individualistic and patient-specific research. Recent progress in human-induced pluripotent stem cell (iPSC) technology provides a novel platform for modeling ASDs for studying ...
Salima Akter, Tae Gyu Choi, Minh Nam Nguyen, Abel Matondo et al.
// Salima Akter 1 , Tae Gyu Choi 1 , Minh Nam Nguyen 1 , Abel Matondo 1 , Jin-Hwan Kim 1 , Yong Hwa Jo 1 , Ara Jo 1 , Muhammad Shahid 1 , Dae Young Jun 1 , Ji Youn Yoo 1 , Ngoc Ngo Yen Nguyen 1 , Seong-Wook Seo 1 , Liaquat Ali 2 , Ju-Seog Lee 3 , Kyung-Sik Yoon 1 , Wonchae Choe 1 , Insug Kang 1 , Jo...
Hee Yul Lee, Du Yong Cho, Kyeong Jin Jang, Jin Hwan Lee et al.
The present study documents the changes in the γ-aminobutyric acid (GABA), the total phenolic (TP), total flavonoid (TF), and isoflavone contents, the antioxidant activities and the digestive enzyme inhibition during the solid lactic acid fermentation of isoflavone-enriched soybean leaves (IESLs) wi...
Jin Hwan Lee, Hee Yul Lee, Du Yong Cho, Min Ju Kim et al.
Abstract An organophosphorus (OP) insecticide-mineralizing strain, Lactobacillus plantarum WCP931, harboring a new OP hydrolase (opdC) gene, was isolated during kimchi (Korean traditional food) fermentation. Strain WCP931 exhibited a significant survival rate of 51 to 96% under artificial gastric ac...
Melbourne Rio Talactac, Mohammed Yousuf Elahi Chowdhury, Min-Eun Park, Prasanna Weeratunga et al.
In order to identify new potential antiviral agents, recent studies have advocated thorough testing of herbal medicines or natural substances that are traditionally used to prevent viral infections. Antiviral activities and the mechanism of action of the total aqueous extract preparation of KIOM-C, ...
Chung Eun Hwang, Md. Azizul Haque, Jin Hwan Lee, Ok Soo Joo et al.
In this study, soy-powder yogurt (SPY) with enhanced levels of γ-aminobutyric acid (GABA) and isoflavone aglycone was produced from sprouting high-protein soybeans (HPSs). The fermented steam-HPS sprouts (0 to 4 cm) were fermented (72 h) with Lactobacillus brevis, and the total free amino acids (FAA...
Hyo Jun Lee, Shil Jin, Hyoun-Joo Kim, Mohammad Shamsul Alam Bhuiyan et al.
Previous studies demonstrated that polymorphisms in the μ-calpain (CAPN1) and calpastatin (CAST) genes had significant effects on meat tenderness in different cattle populations. The aim of this study was to validate the potential association of seven single nucleotide polymorphisms (SNPs) harbored ...
Du-Yong Cho, Hee Yul Lee, Jong-Bin Jeong, Jiho Lee et al.
We studied the changes induced in pH, acidity, brix, reducing sugar, soluble protein, nutritional components, primary metabolites, and antioxidant activities of isoflavone-enriched soybean leaf during the different stages involved in Tricholoma matsutake mycelia fermenting. We found that total fatty...
Su young Hong, Dong-Hee Lee, Jin‐Hwan Lee, Md. Azizul Haque et al.
The cyclic lipopeptide produced from Bacillus pumilus strain HY1 was isolated from Korean soybean sauce cheonggukjang. The chemical structures of the surfactin isomers were analyzed using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and electrospray ion...
Dong Hwan Lee, M. Hasanuzzaman, Daeho Kwon, Hyeyoung Choi et al.
BACKGROUND: The effect of drugs on ATP-binding cassette transporters, especially permeabilityglycoprotein (P-gp), is an important consideration during new anti-cancer drug development. OBJECTIVE: In this context, the effects of a newly synthesized artemisinin derivative, 10-(4-phenyl-1H-1,2,3- triaz...
Hee Yul Lee, Md. Azizul Haque, Du Yong Cho, Jong Bin Jeong et al.
In this study, the microbial diversity, amino acid (FAA), and biological activities of household doenjang (HDJ) from four different regions and commercial doenjang (CDJ) four manufacturers were analyzed. And volatile flavor compound (VFC) and isoflavone profiles were analyzed using gas chromatograph...