Paolo Zanoni, Sumeet A. Khetarpal, Daniel B. Larach, William Hancock‐Cerutti et al.
Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL) cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a lower risk of coronary heart disease (CHD). Mice that have depleted Scarb1 (SR-BI knockout mice) have markedly elevated HDL-C l...
Monika Karmin, Lauri Saag, Mário Vicente, Melissa A. Wilson Sayres et al.
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ...
Luca Pagani, Daniel J. Lawson, Evelyn Jagoda, Alexander Mörseburg et al.
High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, the availability of high-resolution genomic data has led to the development of new methodologies for infe...
Mihai Pop, Alan W. Walker, Joseph N. Paulson, Brianna Lindsay et al.
BACKGROUND: Diarrheal diseases continue to contribute significantly to morbidity and mortality in infants and young children in developing countries. There is an urgent need to better understand the contributions of novel, potentially uncultured, diarrheal pathogens to severe diarrheal disease, as w...
Joris Deelen, Marian Beekman, Hae‐Won Uh, Linda Broer et al.
The genetic contribution to the variation in human lifespan is ∼ 25%. Despite the large number of identified disease-susceptibility loci, it is not known which loci influence population mortality. We performed a genome-wide association meta-analysis of 7729 long-lived individuals of European descent...
Brianna Lindsay, John B. Ochieng, Usman N. Ikumapayi, Aliou Touré et al.
Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, with ...
Simone J.C.F.M. Moorlag, Vasiliki Matzaraki, Jelmer H. van Puffelen, Charlotte van der Heijden et al.
Innate immune cells are able to build memory characteristics via a process termed "trained immunity." Host factors that influence the magnitude of the individual trained immunity response remain largely unknown. Using an integrative genomics approach, our study aimed to prioritize and understand the...
Brianna Lindsay, Joe Oundo, M. Anowar Hossain, Martín Antonio et al.
Pathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia coli infection. We analyzed 3,035 stool specimens (1,735 nondiarrheal and 1,300 ...
Brianna Lindsay, Mihai Pop, Martín Antonio, Alan W. Walker et al.
Cultivation-based assays combined with PCR or enzyme-linked immunosorbent assay (ELISA)-based methods for finding virulence factors are standard methods for detecting bacterial pathogens in stools; however, with emerging molecular technologies, new methods have become available. The aim of this stud...
A-M Mihai
Breast cancer has surpassed lung cancer as the most common type of cancer globally, representing approximately 25% of all cancer cases and leading in cancer-related mortality among women. In Romania, breast cancer accounts for 26.9% of all female cancer diagnoses, with an increasing incidence and si...
Mihail Baša, Aleksandar Sovtić
Acute respiratory infections are the most common group of infective diseases in the pediatric population. Although the improvement of health care and vaccination program has led to a significant reduction in the incidence of certain respiratory infections, the combination of a high prevalence in vul...
Connie Snyder Mick
By bringing together scholars from the United States, Bangladesh, Saudi Arabia, the United Kingdom, and Indonesia, Poverty and Public Policy looks at new poverty issues and policy solutions. The third issue of 2025 collects perspectives on different financial challenges, including policies and techn...
Melissa Fuster
It has been way too long since we entered the so-called “new normal” life under a global pandemic. At Gastronomica, our editorial letters have documented the inevitable influence of these transitions, with each new issue chronicling how our worlds continue to be transformed. This editorial letter, a...
James Heckman, P Edward, Kevin Lazear, Murphy et al.
Previous article FreeIndex to Volume 126PDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinked InRedditEmailQR Code SectionsMoreArticles and NotesAguiar, Luis, and Joel Waldfogel. Quality Predictability and the Welfare Benefits from New...
Elisabeta Popa
Poster: ECR 2016 / C-1222 / Inflammatory breast cancer- the real face of what you actually see by: E. V. Popa 1, M. Lesaru2, M. Mihai2; 1Braila/RO, 2BUCHAREST/RO