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Results for “"Saikat Mitra"”

16+ results

Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity

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Saikat Mitra, Arka Chakraborty, Abu Montakim Tareq, Talha Bin Emran et al.

Journal: Journal of King Saud University - ScienceYear: 2022Citations: 1941

Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in the atmosphere, and ability to accumulate in the human body via bioaccumulation. The pollution of terrestrial and aquatic ecosystems with toxic heavy metals is a major environmental concern that has consequenc...

Physical SciencesEnvironmental ScienceHealth, Toxicology and MutagenesisOpen Access
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Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

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Tanvir Mahtab Uddin, Arka Chakraborty, Ameer Khusro, BM Redwan Matin Zidan et al.

Journal: Journal of Infection and Public HealthYear: 2021Citations: 1237

Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-molecular-weight bioactive agents have also been used for a variety of other medicinal applications. In the battle against microbes, antibiotics have certainly been a blessing to human civilization by savin...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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Multidrug Resistance in Cancer: Understanding Molecular Mechanisms, Immunoprevention and Therapeutic Approaches

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Talha Bin Emran, Asif Shahriar, Aar Rafi Mahmud, Tanjilur Rahman et al.

Journal: Frontiers in OncologyYear: 2022Citations: 541

Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. ...

Health SciencesMedicineOncologyOpen Access
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Exploring the Journey of Zinc Oxide Nanoparticles (ZnO-NPs) toward Biomedical Applications

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Fahadul Islam, Sheikh Shohag, Md Jalal Uddin, Md. Rezaul Islam et al.

Journal: MaterialsYear: 2022Citations: 379

The field of nanotechnology is concerned with the creation and application of materials having a nanoscale spatial dimensioning. Having a considerable surface area to volume ratio, nanoparticles have particularly unique properties. Several chemical and physical strategies have been used to prepare z...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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Berberine as a Potential Anticancer Agent: A Comprehensive Review

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Abdur Rauf, Tareq Abu‐Izneid, Anees Ahmed Khalil, Muhammad Imran et al.

Journal: MoleculesYear: 2021Citations: 283

Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound. T...

Health SciencesMedicinePharmacologyOpen Access
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Superoxide dismutase: an updated review on its health benefits and industrial applications

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Mohammad Nazmul Islam, Abdur Rauf, Fowzul Islam Fahad, Talha Bin Emran et al.

Journal: Critical Reviews in Food Science and NutritionYear: 2021Citations: 278

), are toxic or can create oxidative stress in cells, a response involved in the pathogenesis of numerous diseases depending on their concentration, location, and cellular conditions. Superoxide dismutase (SOD) activities as an endogenous and exogenous cell defense mechanism include the potential us...

Health SciencesNursingNutrition and Dietetics
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Role of Inflammatory Cytokines in COVID-19 Patients: A Review on Molecular Mechanisms, Immune Functions, Immunopathology and Immunomodulatory Drugs to Counter Cytokine Storm

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Ali A. Rabaan, Shamsah H. Al-Ahmed, Javed Muhammad, Amjad Khan et al.

Journal: VaccinesYear: 2021Citations: 256

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious tentacles of the disease have been disseminated worldwide with unknown complications and repercussions. Advanced COVID-19 syndrome is ...

Health SciencesMedicineInfectious DiseasesOpen Access
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The Gut Microbiota (Microbiome) in Cardiovascular Disease and Its Therapeutic Regulation

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Md. Mominur Rahman, Fahadul Islam, Md. Harun- Or-Rashid, Abdullah Al Mamun et al.

Journal: Frontiers in Cellular and Infection MicrobiologyYear: 2022Citations: 240

In the last two decades, considerable interest has been shown in understanding the development of the gut microbiota and its internal and external effects on the intestine, as well as the risk factors for cardiovascular diseases (CVDs) such as metabolic syndrome. The intestinal microbiota plays a pi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Regulatory T cells (Tregs) and their therapeutic potential against autoimmune disorders – Advances and challenges

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T. K. Goswami, Mithilesh Singh, Manish Dhawan, Saikat Mitra et al.

Journal: Human Vaccines & ImmunotherapeuticsYear: 2022Citations: 236

Autoimmune diseases are caused when immune cells act against self-protein. This biological self-non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response regulators and play a pivotal role in immune to...

Life SciencesImmunology and MicrobiologyImmunologyOpen Access
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Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications

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Zidan Khan, Nikhil Nath, Abdur Rauf, Talha Bin Emran et al.

Journal: Chemico-Biological InteractionsYear: 2022Citations: 229

Currently, available therapeutic medications are both costly as well as not entirely promising in terms of potency. So, new candidates from natural resources are of research interest to find new alternative therapeutics. A well-known combination is a β-sitosterol, a plant-derived nutrient with antic...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Viral Dynamics and Real-Time RT-PCR Ct Values Correlation with Disease Severity in COVID-19

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Ali A. Rabaan, Raghavendra Tirupathi, Anupam Sule, Jehad Aldali et al.

Journal: DiagnosticsYear: 2021Citations: 228

Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease 2019 (COVID-19). However, many scientists disagree, and it is essential to understand that several factors and variables can cause a false-negative test. In this context, cycle threshold (Ct) values are being ...

Health SciencesMedicineInfectious DiseasesOpen Access
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Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce—A Comprehensive Review

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Min Shi, Jingyu Gu, Hanjing Wu, Abdur Rauf et al.

Journal: AntioxidantsYear: 2022Citations: 226

Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from food to other specific uses. There are different types in the lettuce group for consumers to choose from. Additionally, lettuce is an excellent source of bioactive compounds such as polyphenols, carotenoids, ...

Health SciencesMedicineBiochemistryOpen Access
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Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

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Arka Chakraborty, Saikat Mitra, Trina Ekawati Tallei, Abu Montakim Tareq et al.

Journal: LifeYear: 2021Citations: 208

Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most commonly used as an anti-inflammatory agent, though scientists have also discovered its potential as an an...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Honokiol: A review of its pharmacological potential and therapeutic insights

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Abdur Rauf, Ahmed Olatunde, Muhammad Imran, Fahad A. Alhumaydhi et al.

Journal: PhytomedicineYear: 2021Citations: 180

Background Honokiol is a pleiotropic compound which been isolated from Magnolia species such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia grandiflora is used in traditional medicine for the treatment of various diseases. Purpose The objective of this review is to summariz...

Health SciencesMedicineRehabilitation
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Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications

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Noor-E-Tabassum, Rajib Das, Mashia Subha Lami, Arka Chakraborty et al.

Journal: Evidence-based Complementary and Alternative MedicineYear: 2022Citations: 179

Ginkgo biloba is an ancient plant species that is thought to provide a variety of health benefits to living organisms and contains plenty of bioactive components, making it a chemically diversified plant. G. biloba has been shown to have a variety of medicinal and pharmacological properties, includi...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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