Zhixian Zhu, Dan Wu, Shuang Li, Han Yu et al.
A polymer-film inertial microfluidic jigsaw (PIMJ) sorter with trapezoidal spiral channels using the jigsaw puzzle method was proposed to realize precise and high-throughput rare cell separation. The PIMJ sorter was fabricated by assembling laser-patterned polymer-film layers of different thicknesse...
Jianxiong Zhu, Shanling Ji, Zhihao Ren, Wenyu Wu et al.
Isopropyl alcohol molecules, as a biomarker for anti-virus diagnosis, play a significant role in the area of environmental safety and healthcare relating volatile organic compounds. However, conventional gas molecule detection exhibits dramatic drawbacks, like the strict working conditions of ion mo...
Yuan Jia, Hao Sun, Xiao Li, Dongke Sun et al.
Rapid, disposable, point-of-care (POC) oral fluid testing has gained considerable attention in recent years as saliva contains biomarker and components of the serum proteome that offer important information on both oral and systemic disease. Microfluidic paper-based analytical devices (μPADs) couple...
Chen Yao, Kefan Guo, Lin Jiang, Shu Zhu et al.
Cell deformability plays an important role in cellular processes and functions, including cell growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at the single-cell level has attracted great interest in biomedicine owing to its importance in various applicat...
Nan Xiang, Zhonghua Ni
Conventional batch-top cell sorters are often bulky and expensive, and miniaturized microfluidic sorters available mostly require field generators and electricity-powered pumping systems. Therefore, the development of a low-cost, portable cell sorter that can be used in low resource settings is esse...
Min Gao, Pengli An, Honghong Rao, Zhengrong Niu et al.
Herein, a simple strategy for constructing activity-controllable nanozymes is proposed based on the glutathione (GSH)-gated surface chemistry of citrate-capped Pt nanoparticles (PtNPs). PtNPs have been shown to have oxidase-like activity that can effectively catalyze the oxidation of 3,3',5,5'-terta...
Zhixian Zhu, Yixuan Zhang, Wenjun Zhang, Dezhi Tang et al.
The carbohydrate antigen 19-9 (CA19-9) is commonly used as a representative biomarker for pancreatic cancer (PC); however, it lacks sensitivity and specificity for early-stage PC diagnosis. Furthermore, some patients with PC are negative for CA19-9 (<37 U/mL), which introduces additional limitations...
Yunfei Chen, Juekuan Yang, Xiaohui Wang, Zhonghua Ni et al.
Energy dissipation due to friction in telescopic carbon nanotubes is modeled by molecular dynamics over a wide temperature range. The energy dissipation or the friction force between the inner and outer tubes is strongly related to thermal effects and shows a minimum as temperature increases. At ult...
Muqing Liu, Yuan Tian, Jie Cheng, Yi Zhang et al.
For its unique flexibility, self-expandable braided stent has been wildly used in the treatment of peripheral vascular diseases, such as the superficial femoral artery stenosis. With the application of bioabsorbable polymer materials, stent braided by polymer filaments is explored, and expected to m...
Dezhi Tang, Lin Jiang, Nan Xiang, Zhonghua Ni
In this paper, a microfluidic impedance cytometer (MIC) was employed to analyze the dielectric properties of human white blood cells (WBCs) and four tumor cell lines and realize the label-free identification of cell types. The impedance of cells was detected using an asymmetric serpentine microchann...
Tianyi Lu, Meng Sun, Yuxuan Zhou, Weilong Tu et al.
Typical anti-infection strategies, such as antibiotics and other antibacterial nanomaterials, are effective in preventing bacterial infections during the wound healing process. Additionally, electrical stimulation (ES) can also inhibit bacterial growth and facilitate skin wound repair. However, self...
Shu Zhu, Xiaozhe Zhang, Mu Chen, Dezhi Tang et al.
We report here an easy-fabricated and disposable polymer-film microfluidic impedance cytometer (PMIC) integrated with inertial focusing and parallel facing electrodes for cell sensing. The cells are first focused in an asymmetric serpentine channel, and then their impedance signals are measured when...
Xiao Li, Man Zhang, Yujie Hu, Jian Xu et al.
In this study, cobalt oxides functionalized MoS 2 /reduced graphene oxide was synthesized via a facile one-pot hydrothermal approach. Morphology and crystal structure of this ternary nanoarchitecture were characterized through scanning electron microscopy, transmission electron microscopy, Raman spe...
Rixin Hua, Yuan Tian, Jie Cheng, Gensheng Wu et al.
Poly(L-lactic acid) (PLLA) is currently the bioresorbable polymer of choice for vascular stents with its superior biocompatibility and mechanical properties. However, it is still difficult to enhance the radial supporting capacity of PLLA stents without increasing the strut thickness. In this study,...
Zhonghua Xue, Hou H, Honghong Rao, Chenxian Hu et al.
A green strategy for assembling graphene films on various carbon-based substrates and its significant electrocatalytic activity toward nitrite oxidation.