Wenju Cai, Lixin Wu, Matthieu Lengaigne, Tim Li et al.
The El Niño-Southern Oscillation (ENSO), which originates in the Pacific, is the strongest and most well-known mode of tropical climate variability. Its reach is global, and it can force climate variations of the tropical Atlantic and Indian Oceans by perturbing the global atmospheric circulation. L...
Md. Abdul Mazid, Carl Ward, Zhiwei Luo, Chuanyu Liu et al.
After fertilization, the quiescent zygote experiences a burst of genome activation that initiates a short-lived totipotent state. Understanding the process of totipotency in human cells would have broad applications. However, in contrast to in mice 1,2 , demonstration of the time of zygotic genome a...
Yongqiang Chen, Pengcheng Li, Ning Pan, Rong Gao et al.
<h3>Background</h3> CD4<sup>+</sup> T cells are critical effectors of anti-tumor immunity, but how tumor cells influence CD4<sup>+</sup> T cell effector function is not fully understood. Tumor cell-released autophagosomes (TRAPs) are being recognized as critical modulators of host anti-tumor immunit...
Zengying Ma, Yao Luo, Peng Wu, Junwen Zhong et al.
Abstract Developing high‐performance electrocatalysts for urea production using CO 2 and N 2 holds great potential to mitigate environmental pollution and energy crisis. In this study, 26 kinds of quadruple TM 2 B 2 ensembles supported on porous C 2 N monolayer are designed as the potential electro...
Fang Tian, Pengjun Jiang, Min Wu, Yun Xing et al.
Myeloid-derived suppressor cells (MDSCs) are a significant obstacle for immunotherapy of cancer. It is of great clinical relevance to study the mechanism of MDSCs accumulation in mouse spleens and establish a stable method to obtain high-purity MDSCs in vitro for further research. Here, we establish...
Qingyun Huang, Cong Wu, Senlin Hou, Kuanming Yao et al.
Underneath the ear skin there are rich vascular network and sensory nerve branches. Hence, the 3D mapping of auricular electrophysiological signals can provide new biomedical perspectives. However, it is still extremely challenging for current sensing techniques to cover the entire ultra-curved auri...
Yiting Wei, J Chen, Yunpeng Zhang, Ying Liu et al.
Chemotherapy induces cancer cell apoptosis and the release of apoptotic bodies (ABs) that are poorly immunogenic or immunosuppressive, creating a major barrier to the success of co-administered or second-line immunotherapies. Here, we found reduced circulating levels of thymosin alpha-1 (Tα-1), a ke...
Zhijun Jiao, Pengtianhao Wu, Biyan Chen, Zhimei Zhang et al.
Accurate and timely flood monitoring is critical for effective disaster management. Remote sensing observations offer large scale monitoring; however, they frequently suffer from observational gaps caused by cloud cover, limited swaths, and extended revisit cycles, severely hindering continuous trac...
Zhijun Jiao, Zhimei Zhang, Biyan Chen, Zelang Miao et al.
Monitoring large-scale floods and tracking their evolution are essential for effective disaster response, particularly in regions where floods have widespread and dynamic impacts. Satellite-based flood detection using Synthetic Aperture Radar (SAR) and optical data faces challenges such as low spati...
Fuyan Wang, Wei Zhang, Yujie Qiao, Depeng Shi et al.
Wuhong Tan, Xiaoyang Du, Jian Liu, Lian-Bang Zhai et al.
OBJECTIVE: To investigate the effect of a traditional Chinese medicine compound (CTMC) on chronic heart failure (CHF) in guinea-pigs. METHODS: The CHF of guinea-pigs were induced by repeated injection of hyodemic isoproterenol. The hemodynamics, organ (heart, lung, liver and kidney)/body weight rati...