Md. Enamul Kabir Talukder, Md. Farhan Atif, Noimul Hasan Siddiquee, Sohanur Rahman et al.
Noimul Hasan Siddiquee, Md. Ifteker Hossain, Md Enamul Kabir Talukder, Syed Afnan Arefin Nirob et al.
Ebola, one of the deadliest known infectious diseases, was the root of epidemics in Western Africa from 2013 to 2016. Like other deadly viruses in the family Filoviridae with a high fatality rate, this virus also causes hemorrhagic fever. As a result, the Ebola virus (EBOV) represents a threat to gl...
Noimul Hasan Siddiquee, Salina Malek, Afsan Ara Tanni, Israt Jahan Mitu et al.
Global urbanization and the growing geographic range of Aedes mosquitoes are the leading causes of the increase in Chikungunya infections, and the lack of a particular antiviral therapy for the disease is a cause of great concern. This article represents the research done so far to find small compou...
Md. Enamul Kabir Talukder, Md. Aktaruzzaman, Noimul Hasan Siddiquee, Sabrina Islam et al.
Background: Rearranged during transfection (RET), an oncogenic protein, is associated with various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer (PTC), pancreatic cancer, medullary thyroid cancer (MTC), breast cancer, and colorectal cancer. Dysregulation of RET cont...
Noimul Hasan Siddiquee, Md. Ifteker Hossain, Farhana Mansoor Priya, Saira Azam et al.
The rare zoonotic Borna disease virus (BDV) causes fatal neurological disease in various animals, with a high mortality rate exceeding 90% in central Europe. However, unlike most viruses, it establishes persistent infections within the host cell nucleus, hindering treatment. As successful BDV treatm...
Noimul Hasan Siddiquee, Afsan Ara Tanni, Nikkon Sarker, Shahadul Hassan Sourav et al.
Human cytomegalovirus (HCMV) is an important opportunistic pathogen that is the most significant viral cause of congenital birth abnormalities and is responsible for a high morbidity and death rate in immunocompromised patients. HCMV's rising severity and the limitations of current vaccines in preve...
Otun Saha, Noimul Hasan Siddiquee, Rahima Akter, Nikkon Sarker et al.
The Nipah virus (NiV) belongs to the Henipavirus genus is a serious public health concern causing numerous outbreaks with higher fatality rate. Unfortunately, there is no effective medication available for NiV. To investigate possible inhibitors of NiV infection, we used in silico techniques to disc...
Saurav Kumar Mishra, Noimul Hasan Siddiquee, Chirag Patel, Neeraj Kumar et al.
Noimul Hasan Siddiquee, Md. Enamul Kabir Talukder, Ezaz Ahmed, Labiba Tasnim Zeba et al.
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family, a non-segmented negative-strand RNA virus. This article represents the computer-aided drug design (CADD) approach for identifying drug-like compounds that prevent the MARV virus disease by inhibiting nucleoprotein, whi...
Noimul Hasan Siddiquee, Shanjida Akter Joyoti, Bushra Binte Zaker, Mansura Akter Eva et al.
West Nile virus is an arbovirus primarily spread by mosquitoes, which are the principal carriers and belong to the Flaviviridae category. This widespread disease lacks specific treatments despite its potential lethality, urgently demanding novel pharmaceutical research and development aims to preven...
Mahmudul Hasan, Md. Ifteker Hossain, Noimul Hasan Siddiquee, Ezaz Ahmed et al.
Proton pump inhibitors are essential for treating moderate-to-severe gastroesophageal reflux, peptic ulcers, esophagitis, and related conditions by increasing gastric pH and inhibiting hydrogen ion discharge into the stomach. However, prolonged use may lead to adverse effects along with reduced effi...
Noimul Hasan Siddiquee, Md. Shiful Islam Sujan, Tasnuva Islam Dremit, Ekramul Hasan Rahat et al.
ABSTRACT Cryptococcus neoformans causes cryptococcal meningitis, which is lethal to immune‐compromised people, especially AIDS patients. This study employed diverse in silico techniques to find the best phytochemical to block farnesyltransferase (FTase). Based on molecular docking, the top two compo...
Abdullah Al Siam, Avijit Kumer Paul, Shanjida Akter Joyoti, Md. Ifteker Hossain et al.
Fusarium solani, an Ascomycota filamentous fungus species, causes shell disease or mycotic infections in wild and farmed shrimps. It causes black gill disease in shrimps, which has no specific treatments, so cutting-edge pharmaceutical research to prevent glutamine synthetase is needed to stop it an...
Nowshin Tabassum, Md. Shorif Hossan, Md. Mujahidul Islam, Mahmudul Hasan et al.
Colorectal cancer (CRC) poses a significant global health issue. It ranks as the third most common type of cancer and the second leading cause of cancer-related deaths. Among the molecular factors driving its progression, cyclin-dependent kinase 2 (CDK2) plays a key role. CDK2 is a protein kinase es...
Sarkar M. A. Kawsar, Samiah H. Al-Mijalli, Bouzid Gassoumi, Emad M. Abdallah et al.
Background/Objectives: Nucleoside precursors and derivatives play pivotal roles in the development of antimicrobial and antiviral therapeutics. The 2022 global outbreak of monkeypox (Mpox) across more than 100 nonendemic countries underscores the urgent need for novel antiviral agents. This study ai...