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Field: Plant biochemistry and biosynthesis

Phytostilbenes as agrochemicals: biosynthesis, bioactivity, metabolic engineering and biotechnology

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Philippe Jeandet, Alessandro Vannozzi, Eduardo Sobarzo‐Sánchez, Md. Sahab Uddin et al.

Journal: Natural Product Reports
Year: 2020
Citations: 100

Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes represent an emblematic group of molecules among natural compounds. Ever since their discovery as antifungal compounds in plants and their ascribed role in human health and disease, phytostilbenes have never ceas...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Secondary Metabolites: Secondary Metabolic Products Consisting of C and H; C, H, and O; N, S, and P Elements; and O/N Heterocycles

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A. N. M. Alamgir

Journal: Progress in drug researchYear: 2018Citations: 92
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol

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Abdullah Al Mamun Sohag, Md. Tahmeed Hossain, Md. Arifur Rahaman, Papia Rahman et al.

Journal: PhytomedicineYear: 2022Citations: 73

BACKGROUND Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in many fruits and vegetables, which is highly investigated for its pharmacological effect and benefit to human health...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Cold stress improves the production of artemisinin depending on the increase in endogenous jasmonate

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Wanhong Liu, Huanyan Wang, Yu‐Pei Chen, Shunqin Zhu et al.

Journal: Biotechnology and Applied BiochemistryYear: 2016Citations: 73

Previous publications reported that the artemisinin level was increased in Artemisia annua following a night-frost period. However, the molecular mechanism was not clear. In this study, we found that exogenous jasmonate (JA) effectively enhanced the freezing tolerance of A. annua. The JA biosyntheti...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Antimicrobial Diterpenes: Recent Development From Natural Sources

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Poushali Saha, Fahad Imtiaz Rahman, Fahad Hussain, S. M. Abdur Rahman et al.

Journal: Frontiers in PharmacologyYear: 2022Citations: 69

Antimicrobial resistance has been posing an alarming threat to the treatment of infectious diseases over the years. Ineffectiveness of the currently available synthetic and semisynthetic antibiotics has led the researchers to discover new molecules with potent antimicrobial activities. To overcome t...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Optimization of salicylic acid and chitosan treatment for bitter secoiridoid and xanthone glycosides production in shoot cultures of Swertia paniculata using response surface methodology and artificial neural network

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Prabhjot Kaur, Raghbir Chand Gupta, Abhijit Dey, Tabarak Malik et al.

Journal: BMC Plant BiologyYear: 2020Citations: 63

Abstract Background In this study, response surface methodology (RSM) and artificial neural network (ANN) was used to construct the predicted models of linear, quadratic and interactive effects of two independent variables viz. salicylic acid (SA) and chitosan (CS) for the production of amarogentin ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Phytoconstituents—Active and Inert Constituents, Metabolic Pathways, Chemistry and Application of Phytoconstituents, Primary Metabolic Products, and Bioactive Compounds of Primary Metabolic Origin

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A. N. M. Alamgir

Journal: Progress in drug researchYear: 2018Citations: 63
Life SciencesBiochemistry, Genetics and Molecular BiologyBiotechnology
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Constituents of Peel and Leaf Essential Oils of Citrus Medica L

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Mohammad Nazrul Islam Bhuiyan, Jaripa Begum, Pranab K Sardar, Mohammad Sharifur Rahman

Journal: Journal of Scientific ResearchYear: 2009Citations: 62

The chemical constituents of leaf and peel essential oil of Citrus medica L. were analysed by gas chromatography mass spectroscopy (GC-MS). Nineteen components accounting for 99.9% of the oil were identified in leaf oil. The major constituents are erucylamide (28.43%), limonene (18.36%) and citral (...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus

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Asif Abdullah, Partha Biswas, Md. Sahabuddin, Afiya Mubasharah et al.

Journal: Journal of ChemistryYear: 2023Citations: 61

Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot generate necessary insulin or does not act in response to it, accordingly, ensuing in discordantly high blood sugar (glucose) levels. Diabetes mellitus can lead to systemic dysfunction in the multiorgan system, i...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Variations in fat content and lipid class composition in ten different mango varieties

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M. A. Ali, M. A. Gafur, M. S. Rahman, GM Ahmed

Journal: Journal of the American Oil Chemists SocietyYear: 1985Citations: 57

Abstract The kernels of 10 different mango varieties were extracted. The physico‐chemical characteristics and lipid class composition of fats were studied. The fat content of mango kernels grown under the soil and climatic conditions of Bangladesh varied from 7.1% to 10%, depending on the variety. T...

Life SciencesBiochemistry, Genetics and Molecular BiologyBiochemistry
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Supercritical carbon dioxide extraction of β-carotene and α-tocopherol from pumpkin: a Box–Behnken design for extraction variables

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Xiudong Wang, Chen Wang, Xianjun Zha, Yanan Mei et al.

Journal: Analytical MethodsYear: 2016Citations: 54

In this study, supercritical fluid extraction with carbon dioxide was applied to achieve a successful extraction of both β-carotene and α-tocopherol from pumpkin.

Health SciencesMedicineBiochemistry
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Editorial: Phenylpropanoid biosynthesis in plants

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Abdur Rahim, Xuebin Zhang, Nicola Busatto

Journal: Frontiers in Plant ScienceYear: 2023Citations: 51

EDITORIAL article Front. Plant Sci., 16 June 2023Sec. Plant Metabolism and Chemodiversity Volume 14 - 2023 | https://doi.org/10.3389/fpls.2023.1230664

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Diterpenes/Diterpenoids and Their Derivatives as Potential Bioactive Leads against Dengue Virus: A Computational and Network Pharmacology Study

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Rasel Ahmed Khan, Rajib Hossain, Abolghasem Siyadatpanah, Khattab Al-Khafaji et al.

Journal: MoleculesYear: 2021Citations: 50

Dengue fever is a dangerous infectious endemic disease that affects over 100 nations worldwide, from Africa to the Western Pacific, and is caused by the dengue virus, which is transmitted to humans by an insect bite of Aedes aegypti. Millions of citizens have died as a result of dengue fever and den...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Structure-based identification of potent VEGFR-2 inhibitors from in vivo metabolites of a herbal ingredient

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Raju Dash, Md. Junaid, Sarmistha Mitra, Md. Arifuzzaman et al.

Journal: Journal of Molecular ModelingYear: 2019Citations: 50

Vascular endothelial growth factor receptor-2 (VEGFR-2) is one of the regulatory elements of angiogenesis that is expressed highly in various diseases and is also essential for solid tumor growth. The present study was aimed at identifying potent inhibitors of VEGFR-2 by considering herbal secondary...

Life SciencesPharmacology, Toxicology and PharmaceuticsToxicology
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Metabolic profiling of phenolics of the extracts from the various parts of blackberry plant (Syzygium cumini L.) and their antioxidant activities

Verified

Md. Abdul Halim, Kawser Alam Kanan, Towrin Nahar, Md Jiaur Rahman et al.

Journal: LWTYear: 2022Citations: 49

The phenolic metabolites were extracted from the defatted leaves, seeds and pulp of blackberry using 80% ethanol. The phenolic profiles and antioxidant activities of the extracts so obtained were then evaluated. In addition, metabolic pathway determination was performed by metabo Analyst as well as ...

Health SciencesMedicineBiochemistryOpen Access
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